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Multiple Choice

Name a genetic condition that can increase the likelihood of an aneurysm.

The main idea here is that certain inherited connective tissue disorders can weaken the aorta and raise the risk of an aneurysm. Marfan syndrome does this most clearly: mutations in fibrillin-1 cause weaker connective tissue, including the walls of the aorta, making dilation and dissection more likely. This explains why people with Marfan require regular aortic imaging and may use medications to reduce stress on the vessel wall. The other conditions involve different cardiovascular issues and are not as strongly linked to aneurysm risk as Marfan.

The main idea here is that certain inherited connective tissue disorders can weaken the aorta and raise the risk of an aneurysm. Marfan syndrome does this most clearly: mutations in fibrillin-1 cause weaker connective tissue, including the walls of the aorta, making dilation and dissection more likely. This explains why people with Marfan require regular aortic imaging and may use medications to reduce stress on the vessel wall. The other conditions involve different cardiovascular issues and are not as strongly linked to aneurysm risk as Marfan.